Multimodal Assessment of Neurobiological Markers for Psychiatric Disorders
NCT01477203 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 289
Last updated 2016-09-14
Summary
MAN-BIOPSY pursues the concrete research question whether novel biological and psycho-physiological clusters or categories can be defined to improve treatment and minimize side effects in psychiatry, based on a synopsis of physiological, behavioural, genetic and endocrinological parameters. One major aspect of our research approach is its focuses on the identification of dysfunctions in fundamental information processing mechanisms and neurocomputational mechanisms, and is not restricted to symptom-oriented tasks.
The main objectives of MAN-BIOPSY are therefore
* to identify biological and psycho-physiological parameters for major depressive disorders and anxiety disorders, and
* to identify predictive markers for treatment response and type/severity of side effects for these disorders.
Conditions
- Major Depressive Disorder (MDD)
- Anxiety Disorder
Interventions
- DRUG
-
Escitalopram
2-4 weeks, 5-10mg, max 20mg
Sponsors & Collaborators
-
Medical University of Vienna
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-11-30
- Primary Completion
- 2016-09-30
- Completion
- 2016-09-30
Countries
- Austria
Study Locations
More Related Trials
-
Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk Youth
NCT02553161 ·Status: COMPLETED ·Phase: NA
-
Study of Neural Responses Induced by Antidepressant Effects
NCT02674529 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Cognitive Dysfunction in MDD Patients
NCT03187093 ·Status: UNKNOWN ·Phase: PHASE4
-
Pharmacokinetic and Pharmacodynamic Effects of Escitalopram Depending on Genetic Polymorphisms of the ABCB1-gene
NCT00550485 ·Status: COMPLETED ·Phase: NA
-
An Efficacy and Safety Study of Escitalopram Long-Term Treatment in Major Depressive Disorder With Associated Anxiety Symptoms
NCT01814098 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Safety of SR58611A in Patients With Major Depressive Disorder
NCT00252330 ·Status: COMPLETED ·Phase: PHASE3
-
Developing New Clinical Management Strategies
NCT02082392 ·Status: COMPLETED ·Phase: PHASE4
-
Mechanisms of Antidepressant Non-Response in Late-Life Depression
NCT01931202 ·Status: COMPLETED ·Phase: NA
-
Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram
NCT00183677 ·Status: COMPLETED ·Phase: PHASE4
-
A Safety and Efficacy Study of Escitalopram on Acute Treatment of Severe Depression
NCT01814085 ·Status: COMPLETED ·Phase: PHASE4
-
Brain Aging and Treatment Response in Geriatric Depression
NCT01902004 ·Status: COMPLETED ·Phase: PHASE4
-
Investigating the Protective Impact of LY-2940094 on Stress-induced Depression- and Anxiety-related Phenotypes in Humans
NCT06786637 ·Status: WITHDRAWN ·Phase: PHASE2
-
The Effect of Escitalopram on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients
NCT02623231 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Neural Responses and Dysphoria: Modulation by a Pharmacological Probe
NCT01101685 ·Status: COMPLETED ·Phase: PHASE4
-
Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety
NCT02818751 ·Status: COMPLETED ·Phase: NA
-
To Assess the Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)
NCT01123707 ·Status: TERMINATED ·Phase: PHASE3
-
Brain GABA Levels and Treatment Response in Major Depressive Disorder
NCT00464711 ·Status: COMPLETED ·Phase: PHASE4
-
Escitalopram as a Mood Stabilizer for Bipolar II Disorder
NCT00156325 ·Status: COMPLETED ·Phase: PHASE2
-
Pre-Treatment Positron Emission Topography Scanning for Increasing Success in Antidepressant Treatment
NCT00456014 ·Status: COMPLETED ·Phase: NA
-
Contact: Developing New Clinical Management Strategies
NCT03812588 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Impact of Escitalopram on Quality of Life and Social Functionality in Patients With Major Depressive Disorder With Anxiety Symptom
NCT01870843 ·Status: COMPLETED ·Phase: PHASE4
-
Escitalopram in Adult Patients With Major Depressive Disorder
NCT00668525 ·Status: COMPLETED ·Phase: PHASE3
-
In Vitro Modeling of Drug-resistant Psychiatric Disorders Using Induced Pluripotent Cells
NCT05887310 ·Status: UNKNOWN
-
Neurobiological Bases of Placebo Response in Major Depressive Disorder
NCT01787240 ·Status: TERMINATED ·Phase: PHASE4
-
Treatment of Depression in Adults
NCT00073697 ·Status: COMPLETED ·Phase: PHASE4