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Valproic Acid, Magnesium Sulphate, Rocuronium Requirement, Postoperative Analgesia

NCT01460563 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2011-12-29

No results posted yet for this study

Summary

The investigators hypothesized that valproic acid will increase rocuronium requirement and MgSO4 infusion would reduce requirement of muscle relaxant in craniotomy patients preloaded with sodium valproate.

Conditions

  • Cerebral Aneurysm

Interventions

DRUG

Magnesium Sulfate

MgSO4 infusion: 50mg/kg bolus followed by continuous infusion

DRUG

0.9% saline

0.9% saline as same dose as MgSO4 as placebo

DRUG

0.9% saline

0.9% saline as same dose as MgSO4 as placebo

Sponsors & Collaborators

  • Seoul National University Bundang Hospital

    lead OTHER

Principal Investigators

  • Sanghwan Do, Doctor · Seoul National University Bundang Hospital

Study Design

Allocation
RANDOMIZED
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-10-31
Primary Completion
2011-12-31
Completion
2011-12-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01460563 on ClinicalTrials.gov