Endothelial Dysfunction in Subjects With History of Premature Coronary Artery Disease
NCT00917527 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 77
Last updated 2012-07-23
Summary
The aim of this prospective study is to investigate the prevalence of endothelial dysfunction in subjects with family history of premature coronary heart disease. At the same time, the effect of atorvastatin in treating subclinical endothelial dysfunction in those patients will be evaluated.
Conditions
Interventions
- DRUG
-
Atorvastatin 40mg/D for 6 weeks to improve endothelial dysfunction
Sponsors & Collaborators
-
Yonsei University
lead OTHER
Principal Investigators
-
Hyuk-Jae Chang, MD, PhD · Cardiology Division, Severance Cardiovascular Hospital, Yonsei University College of Medicine
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- QUADRUPLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-06-30
- Primary Completion
- 2012-11-30
- Completion
- 2013-06-30
Countries
- South Korea
Study Locations
More Related Trials
-
Atorvastatin Pre-Treatment Influences the Risk of Percutaneous Coronary Intervention (PCI) Study 2
NCT01058057 ·Status: UNKNOWN ·Phase: PHASE3
-
The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT)
NCT01341730 ·Status: TERMINATED ·Phase: PHASE4
-
Efficacy of High Dose atorvaSTATIN Loading Before Primary Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction (STATIN STEMI)
NCT00808717 ·Status: COMPLETED ·Phase: PHASE4
-
Atorvastatin Pre-Treatment Influences the Risk of Percutaneous Coronary Intervention Study
NCT00469326 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Short Term, High Dose Atorvastatin Therapy on Periprocedural Myonecrosis and Platelet Inhibition After Percutaneous Coronary Intervention (PCI)
NCT00979940 ·Status: TERMINATED ·Phase: NA
-
Effect of Atorvastatin and Lifestyle Intervention on Progression of Pre-Clinical Atherosclerosis
NCT00723320 ·Status: UNKNOWN ·Phase: NA
-
Cholesterol Goal Attainment Rate and Its Associated Factors Among Dyslipidemic Patients on Lipid-lowering Drug Therapy in Korea
NCT01372956 ·Status: COMPLETED
-
Anti-inflammatory Effect of Atorvastatin in Atherosclerotic Plaques Assessed by FDG-PET Imaging
NCT00920101 ·Status: UNKNOWN ·Phase: PHASE4
-
Index of Microcirculatory Resistance After Drug-Eluting Stent Implantation With High Dose Atorvastatin Loading
NCT01491256 ·Status: UNKNOWN ·Phase: NA
-
Change in Plaque Characteristics With Atorvastatin
NCT00700037 ·Status: COMPLETED ·Phase: PHASE4
-
Atorvastatin for Reduction of Myocardial Damage During Angiography and Its Mechanism Associated With IMR
NCT01761656 ·Status: UNKNOWN ·Phase: PHASE2
-
Statin Effect on Arrhythmogenic Cardiomyopathy Disease Progression (SEARCH)
NCT06922994 ·Status: RECRUITING ·Phase: PHASE2
-
Evaluation of Atorvastatin on Atherosclerosis Composition
NCT00576576 ·Status: COMPLETED ·Phase: NA
-
Efficacy Study of Pioglitazone and Atorvastatin Combination Therapy in Treating Subjects With Elevated Risk for Cardiovascular Disease
NCT00770575 ·Status: COMPLETED ·Phase: PHASE2
-
Statins Evaluation in Coronary Procedures and Revascularization Trial
NCT01448642 ·Status: COMPLETED ·Phase: PHASE4
-
Cerebral and Peripheral Perfusion Pilot Study
NCT00751907 ·Status: COMPLETED ·Phase: PHASE2
-
Further Lipid-Lowering With PCSK9 Inhibitors for Cardiovascular Outcomes in High-Risk Coronary Plaques Assessed by CT Angiography
NCT06863545 ·Status: RECRUITING ·Phase: NA
-
Effect of Atorvastatin on Vascular Inflammation in Type 2 Diabetes
NCT00932048 ·Status: WITHDRAWN ·Phase: NA
-
Effect of Low-dose vs. High-dose Pitavastatin on In-stent Restenosis
NCT02545231 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Atorvastatin on Myonecrosis
NCT00344019 ·Status: TERMINATED ·Phase: PHASE4
-
Research of Resistance to Antiplatelet Agents and Development of Tailored Treatment Model for Patients With Coronary Artery Disease
NCT02121054 ·Status: COMPLETED
-
COmparison and Modification in Neointimal Pattern Assessed by Optical Coherence Tomography With High Versus Moderate Efficacy Statin Treatment After Drug Eluting Stent Implantation: COMPASS Trial
NCT02155530 ·Status: COMPLETED ·Phase: NA
-
Atorvastatin Pre-Treatment Study In Asian Patients With Acute Coronary Syndrome
NCT00728988 ·Status: COMPLETED ·Phase: PHASE4
-
Effects of Celecoxib After Percutaneous Coronary Intervention
NCT00292721 ·Status: COMPLETED ·Phase: PHASE4
-
Mobilization of Endothelial Progenitor Cells Induced by Atorvastatin in Patients With Stable Coronary Artery Disease Treated With Anti-CD 34 Antibodies Coated Stents
NCT00911339 ·Status: TERMINATED ·Phase: PHASE3