Avastin Plus Radiotherapy in Elderly Patients With Glioblastoma
NCT01443676 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 75
Last updated 2016-11-01
Summary
The purpose of this study is to explore the efficacy of bevacizumab combined with radiotherapy compared with radiotherapy alone in the treatment of newly diagnosed glioblastoma in the elderly.
* Trial with medicinal product
Conditions
Interventions
- DRUG
-
Bevacizumab will be added to radiotherapy
- RADIATION
-
Radiation therapy
Radiation therapy
Sponsors & Collaborators
-
University of Zurich
lead OTHER
Principal Investigators
-
01 Studienregister MasterAdmins · UniversitaetsSpital Zuerich
-
Michael Weller, Professor · University Hospital Zurich, Division of Neurology
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-10-31
- Primary Completion
- 2015-08-31
- Completion
- 2016-08-31
Countries
- Switzerland
Study Locations
More Related Trials
-
Radiosurgery Plus Bevacizumab in Glioblastoma
NCT01086345 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
Study of Prognostic Biomarkers of Survival at 6 Months for Patients Treated With Bevacizumab Glioblastomas in First Relapse After Failure of Radiochemotherapy
NCT03144167 ·Status: RECRUITING ·Phase: NA
-
Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma
NCT01849146 ·Status: COMPLETED ·Phase: PHASE1
-
Pyrazoloacridine Followed by Radiation Therapy in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme
NCT00006355 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomas
NCT00597402 ·Status: COMPLETED ·Phase: PHASE2
-
Hyperpolarized Imaging in Diagnosing Participants With Glioma
NCT03739411 ·Status: RECRUITING ·Phase: PHASE1
-
Irinotecan Plus Radiation Therapy Followed By Chemotherapy in Treating Patients With Glioblastoma Multiforme
NCT00027612 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Personalized Radiation Therapy for GBM
NCT03477513 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Radiosurgery and Avastin for Recurrent Malignant Gliomas
NCT01017250 ·Status: COMPLETED ·Phase: NA
-
Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
NCT04047706 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Carboxyamidotriazole + RT in Treating Patients Newly Diagnosed Supratentorial GBM
NCT00004146 ·Status: COMPLETED ·Phase: PHASE2
-
Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma
NCT01386710 ·Status: SUSPENDED ·Phase: PHASE1/PHASE2
-
Effect of Timing of Tumor-Treating Fields Plus Short-Course Radiation
NCT04218019 ·Status: WITHDRAWN ·Phase: NA
-
Hippocampal-Avoiding Whole Brain Irradiation With Simultaneous Integrated Boost for Treatment of Brain Metastases
NCT01414738 ·Status: COMPLETED ·Phase: PHASE2
-
Radiotherapy for Malignant Astrocytomas in the Elderly
NCT00430911 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme
NCT00006386 ·Status: COMPLETED ·Phase: PHASE2
-
Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme
NCT00002545 ·Status: COMPLETED ·Phase: PHASE3
-
Surgery Followed by Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00053183 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Therapy in Treating Patients With Glioblastoma
NCT00019058 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Boost for Newly Diagnosed Glioblastoma Multiforme
NCT00376103 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Computer Planned Radiation Therapy Plus Chemotherapy in Treating Patients With Glioblastoma Multiforme
NCT00003417 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Glutamate Inhibitors in Glioblastoma
NCT05664464 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial
NCT06835803 ·Status: RECRUITING ·Phase: PHASE2
-
Suramin Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00004073 ·Status: COMPLETED ·Phase: PHASE2
-
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
NCT02709226 ·Status: COMPLETED ·Phase: PHASE1