Computer Planned Radiation Therapy Plus Chemotherapy in Treating Patients With Glioblastoma Multiforme
NCT00003417 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2015-11-17
Summary
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Computer systems that allow doctors to create a 3-dimensional picture of the tumor in order to plan treatment may result in more effective radiation therapy. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells.
PURPOSE: Phase I/II trial to study the effectiveness of radiation therapy that has been planned with a computer plus chemotherapy in treating patients who have glioblastoma multiforme.
Conditions
Interventions
- DRUG
-
carmustine
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Radiation Therapy Oncology Group
lead NETWORK
Principal Investigators
-
Jeff M. Michalski, MD · Washington University Siteman Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-09-30
- Primary Completion
- 2004-05-31
Countries
- United States
- Canada
Study Locations
More Related Trials
-
S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma
NCT00017147 ·Status: COMPLETED ·Phase: PHASE3
-
Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma
NCT00003876 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00003996 ·Status: COMPLETED ·Phase: PHASE2
-
Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00099125 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma
NCT00005637 ·Status: COMPLETED ·Phase: PHASE1
-
Suramin Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00004073 ·Status: COMPLETED ·Phase: PHASE2
-
Carmustine in Treating Adults With Recurrent Supratentorial Low-Grade Glioma
NCT00003467 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide and Radiation Therapy With or Without Vatalanib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00128700 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Stereotactic Radiosurgery and Radiation Therapy in Treating Patients With Glioblastoma Multiforme
NCT00253448 ·Status: COMPLETED ·Phase: PHASE2
-
Carmustine Wafers Plus Irinotecan in Treating Patients With Recurrent Supratentorial High Grade Gliomas
NCT00003463 ·Status: COMPLETED ·Phase: PHASE1
-
Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas
NCT00005602 ·Status: COMPLETED ·Phase: PHASE1
-
Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
NCT00052715 ·Status: TERMINATED ·Phase: PHASE2
-
Hypofractionated Stereotactic Radiotherapy in Recurrent Glioblastoma Multiforme
NCT01464177 ·Status: COMPLETED ·Phase: PHASE2
-
Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma
NCT02709226 ·Status: COMPLETED ·Phase: PHASE1
-
Observation or Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Low-Grade Glioma
NCT00003375 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Carboplatin Plus Irinotecan in Treating Patients With Glioblastoma Multiforme
NCT00010036 ·Status: COMPLETED ·Phase: PHASE2
-
Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme
NCT02575027 ·Status: COMPLETED ·Phase: NA
-
Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Glioblastoma
NCT05083754 ·Status: RECRUITING ·Phase: PHASE1
-
Temozolomide and Radiation Therapy in Treating Patients With Gliomas
NCT00114140 ·Status: COMPLETED ·Phase: PHASE2
-
Personalized Radiation Therapy for GBM
NCT03477513 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Radiation Therapy in Treating Patients With Glioblastoma
NCT00019058 ·Status: COMPLETED ·Phase: PHASE1
-
Carmustine in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
NCT00006656 ·Status: UNKNOWN ·Phase: PHASE2
-
Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas
NCT00004259 ·Status: COMPLETED ·Phase: PHASE3
-
Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma
NCT00002806 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma
NCT00003625 ·Status: COMPLETED ·Phase: PHASE1