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Developing Cognitive Training for Tourette Syndrome

NCT01440023 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2015-01-15

No results posted yet for this study

Summary

Many researchers suspect that individuals with Tourette Syndrome (TS) may have a poor cognitive ability (i.e., response inhibition; RI) that is essential to inhibit inappropriate response such as vocal or motor tics. The investigators aim to test whether a well-established behavior therapy for TS can be improved by increasing the individual's RI capabilities. To this end, 20 children will be randomly assigned to behavior therapy with computer-based RI training or behavior therapy with placebo computer-based cognitive training. The investigators will test the hypothesis that computer-based RI training can be a useful addition to the well-established behavior therapy to enhance its therapeutic effect.

Conditions

  • Tourette Syndrome
  • Chronic Tic Disorders

Interventions

BEHAVIORAL

Comprehensive Behavioral Intervention for Tics (CBIT)

CBIT is an 8 session treatment protocol held over 10 weeks. Its core components are implemented across the various therapy sessions. These core components include habit reversal training (HRT), functional assessment/function-based interventions, and a behavioral reward program for the child.

BEHAVIORAL

Computerized Response Inhibition Training

Twice-weekly 45 minute computerized sessions for cognitive training focused on enhancing response inhibition capabilities.

BEHAVIORAL

Computerized Placebo Cognitive Training

Twice-weekly 45 minute computerized sessions for placebo cognitive training, which has been designed to be irrelevant for response inhibition capabilities.

Sponsors & Collaborators

  • Tourette Association of America

    collaborator OTHER

  • University of Wisconsin, Milwaukee

    lead OTHER

Principal Investigators

  • Han Joo Lee, Ph.D. · University of Wisconsin, Milwaukee

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
9 Years
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-08-31
Primary Completion
2014-12-31
Completion
2014-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01440023 on ClinicalTrials.gov