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PPROM Erythromycin Versus Azithromycin

NCT01431248 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 7

Last updated 2013-01-16

No results posted yet for this study

Summary

Preterm Premature Rupture of Membranes (PPROM) is treated with an antibiotic, erythromycin or azithromycin, to prolong pregnancy. Erythromycin is taken for several days and can result in stomach upset in some patients, causing them to stop taking the medication. Therefore, azithromycin is often prescribed instead. Azithromycin is usually taken only once and stomach upset is not seen or greatly reduced. The goal of this study is to see if there is a difference between the antibiotic (azithromycin) compared to the antibiotic (erythromycin) in prolonging pregnancy in patients with Preterm Premature Rupture of Membranes (PPROM). The working hypothesis is that there is no difference in the clinical effectiveness between antibiotic regimens containing te macrolides azithromycin and erythromycin for prolonging latency in PPROM.

Conditions

  • Preterm Premature Rupture of Membranes

Sponsors & Collaborators

  • Indiana University School of Medicine

    collaborator OTHER

  • University of Oklahoma

    lead OTHER

Principal Investigators

  • Eric Knudtson, MD · University of Oklahoma

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-09-30
Primary Completion
2013-01-31
Completion
2013-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01431248 on ClinicalTrials.gov