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Pharmacokinetics of Posaconazole in Allogeneic Transplant Patients With Mucositis

NCT01420562 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 55

Last updated 2024-07-15

No results posted yet for this study

Summary

The goal of this study is to calculate pharmacokinetic parameters and to evaluate the trough levels of posaconazole reached in patients with different stages of mucositis, due to chemotherapy and total body irradiation.

Conditions

  • Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Interventions

PROCEDURE

blood sampling

During posaconazole treatment, blood sampling will occur on day 0 (=day of transplantation), day 7 and 14 to correlate posaconazole exposure to severity of mucositis.

Sponsors & Collaborators

  • Universitaire Ziekenhuizen KU Leuven

    lead OTHER

Principal Investigators

  • Kim Vanstraelen, R.Ph. · Catholic University of Leuven, Faculty of Pharmacy, division Hospital Pharmacy

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-09-30
Primary Completion
2025-03-31
Completion
2025-03-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01420562 on ClinicalTrials.gov