Progression of Early Subclinical Atherosclerosis
NCT01410318 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 4184
Last updated 2021-04-29
Summary
The overall objective of this study is to characterize the prevalence and progression rate of subclinical atherosclerotic lesions and to study their association to the imaging characteristics of atheroma plaques and to the presence of genetic, epigenetic, metabolomic, and environmental factors, including dietary habits, physical activity, biorhythms, psychosocial characteristics, and exposure to environmental pollutants
Conditions
Sponsors & Collaborators
-
Grupo Santander
collaborator UNKNOWN -
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
lead OTHER
Principal Investigators
-
Valentín Fuster, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Antonio I Fernández Ortiz, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Borja Ibañez, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Ginés Sanz, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Jose María Ordovás, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Luis Jesús Jiménez Borreguero, MD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Jose Luis Peñalvo, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Martín Laclaustra, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Ana Dopazo, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Leticia Fernández Friera, PhD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
-
Agustin Mocoroa, MD · Banco Santander
-
Beatriz Lopez Melgar, MD · Centro Nacional de Investigaciones Cardiovasculares Carlos III
Eligibility
- Min Age
- 40 Years
- Max Age
- 54 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-06-14
- Primary Completion
- 2030-06-30
- Completion
- 2030-06-30
Countries
- Spain
Study Locations
More Related Trials
-
Plaque Reversal With Early, Aggressive Lipid Lowering Therapy
NCT05783804 ·Status: RECRUITING
-
Evaluation of Atorvastatin on Atherosclerosis Composition
NCT00576576 ·Status: COMPLETED ·Phase: NA
-
Mechanism and Intervention Research of Atherosclerosis
NCT05437107 ·Status: COMPLETED
-
Identification of CETP as a Marker of Atherosclerosis
NCT02081066 ·Status: COMPLETED ·Phase: NA
-
the Change of CEM and the Prognosis of Coronary Artery Disease in Real Clinical Practice
NCT03473860 ·Status: UNKNOWN
-
Further Lipid-Lowering With PCSK9 Inhibitors for Cardiovascular Outcomes in High-Risk Coronary Plaques Assessed by CT Angiography
NCT06863545 ·Status: RECRUITING ·Phase: NA
-
Protective Effect of Early High Dose stATins On Cardiovascular and Renal Events in Acute Coronary Syndrome
NCT04087200 ·Status: RECRUITING
-
Statins and Risk of Myocardial Infarction in Real Life in France
NCT00679575 ·Status: COMPLETED
-
Statins to Prevent Immune Checkpoint Inhibitor-induced PRogression of AtherosLerosis
NCT06785974 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Effect of Atorvastatin and Lifestyle Intervention on Progression of Pre-Clinical Atherosclerosis
NCT00723320 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus Ezetimibe
NCT00475826 ·Status: UNKNOWN ·Phase: NA
-
the Change of Cholesterol Efflux Capacity and Coronary Artery Disease in Real Clinical Practice
NCT03389529 ·Status: UNKNOWN
-
Atorvastatin for Reduction of Myocardial Damage During Angiography and Its Mechanism Associated With IMR
NCT01761656 ·Status: UNKNOWN ·Phase: PHASE2
-
Effects Of Atorvastatin On Macrophage Activity And Plaque Inflammation Using Magnetic Resonance Imaging
NCT00368589 ·Status: COMPLETED
-
The Effects of Atorvastatin in Patients With Atherosclerosis
NCT00115817 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy Study of p38 Kinase Inhibitor to Treat Patients With Atherosclerosis
NCT00570752 ·Status: COMPLETED ·Phase: PHASE2
-
Statins in Cerebral Blood Flow and Neuronal Activity--A Pilot Study
NCT03411291 ·Status: COMPLETED
-
Change in Plaque Characteristics With Atorvastatin
NCT00700037 ·Status: COMPLETED ·Phase: PHASE4
-
Dietary Intervention to Stop COronary Atherosclerosis in Computed Tomography
NCT02571803 ·Status: UNKNOWN ·Phase: NA
-
Evaluate the Effect of Atorvastatin on Cerebrovascular Reactivity in Mild Cognitive Impairment (MCI)
NCT04765137 ·Status: RECRUITING ·Phase: PHASE2
-
Metabolic and Metagenomic Effects of Intestinal Microbiome Repopulation in Unexplained Atherosclerosis
NCT04410003 ·Status: RECRUITING ·Phase: PHASE1
-
Intensive Lipid-lowering for Plaque and Major Adverse Cardiovascular Events in Low to Intermediate 10-year ASCVD Risk Population
NCT05462262 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome
NCT01223586 ·Status: COMPLETED
-
Effects of Statins on Pro- and Antioxidant Status : Link With Statin-Associated Myopathy.
NCT00285181 ·Status: COMPLETED ·Phase: NA
-
Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy
NCT05802108 ·Status: UNKNOWN ·Phase: PHASE4