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Control of Emergence Blood Pressure During Craniotomy for Tumor Surgery Between Labetolol and Diltiazem

NCT01408524 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 184

Last updated 2014-04-01

No results posted yet for this study

Summary

The purpose of this study is to determine the effectiveness of the antihypertensive drugs in the control of emergence blood pressure after tumor resection craniotomy; compared between labetalol (Avexa) and diltiazem (Herbessor).

Also the investigators seek to determine the effective dose of the antihypertensive drugs and their side effects in Thai population.

Conditions

Interventions

DRUG

Diltiazem

2.5 mg iv q 2-5 min for keeping SBP below 140 mmHg during the emergence

DRUG

Labetalol

2.5 mg iv q 2-5 min for keeping SBP below 140 mmHg during the emergence

Sponsors & Collaborators

  • Mahidol University

    lead OTHER

Principal Investigators

  • Busara - Sirivanasandha, MD · Department of Anesthesiology, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-02-28
Primary Completion
2012-11-30
Completion
2013-12-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01408524 on ClinicalTrials.gov