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An Analysis of Potential Sex Differences in Knee Osteoarthritis

NCT01403207 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2014-03-14

No results posted yet for this study

Summary

This pilot study will use tissues and fluids that are normally discarded during the course of total knee replacement surgery to investigate potential sex differences in knee osteoarthritis. Basic clinical demographic information will be obtained as well as preoperative functional and pain assessment scores, functional tests, and pressure pain threshold measurement. The purpose of the study will be to investigate if any sex differences can be identified in these tissues and to investigate if there appears to be any relationship between these differences and functional scores and tests.

Conditions

Interventions

OTHER

musculoskeletal

Many musculoskeletal conditions are impacted by the chromosomal sex of the patient. While osteoarthritis (OA) is predominant in men younger than 50 years of age, after age 50 the condition is more prevalent in women, particularly post-menopause. This has implications for diagnosis and treatment of OA, as well as for joint replacement.

Sponsors & Collaborators

  • Society of Women's Health Research

    collaborator UNKNOWN

  • University of Calgary

    collaborator OTHER

  • Florida State University

    collaborator OTHER

  • Georgia Institute of Technology

    collaborator OTHER

  • Mary O'Connor

    lead OTHER

Principal Investigators

  • Mary I O'Connor, MD · Mayo Clinic Jacksonville, Chair, Orthopedics

Eligibility

Min Age
65 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-08-31
Primary Completion
2013-06-30
Completion
2014-03-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01403207 on ClinicalTrials.gov