Prevalence of Pneumocystis Jirovecii and of Cytomegalovirus in Bronchial Wash Fluid of Patients Undergoing Bronchoscopy
NCT01395498 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 93
Last updated 2016-07-28
Summary
The purpose of this study is to determine the incidence of the "carriage" state (asymptomatic colonization) with Pneumocystis Jirovecii (Pneumocystic Carinii Pneumonia, PCP) and Cytomegalovirus (CMV)in the human lung. These are pathogens causing pneumonia in patients with suppressed immune system, but not known to cause disease in otherwise normal people. The investigators hypothesis is that a carriage state exists for these two pathogens. To test this hypothesis the investigators will examine bronchoalveolar lavage fluid for genetic material of these two pathogens. The study population will be patients undergoing fiberoptic bronchoscopy and lavage for indications other than diagnosis of a presumed opportunistic infection.
Conditions
- Patients Scheduled for Bronchoscopy
Interventions
- OTHER
-
laboratory testing of PCP and CMV genetic material
laboratory testing of PCP and CMV DNA in bronchoalveolar lavage fluid, CMV PCR in blood+ serology in patients with positive BAL.
Sponsors & Collaborators
-
Carmel Medical Center
lead OTHER
Principal Investigators
-
Yochai Adir, MD · Pulmonology Institute, Carmel Medical Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-07-31
- Primary Completion
- 2013-02-28
- Completion
- 2013-12-31
Countries
- Israel
Study Locations
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