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Selective Digestive Decontamination in Carriers of Carbapenem-resistant Klebsiella Pneumoniae

NCT00753558 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL

Last updated 2010-09-21

No results posted yet for this study

Summary

There is an urgent need to control our current national outbreak of carbapenem-resistant Klebsiella pneumoniae (CRKP). The purpose of this study is to eradicate CRKP gastrointestinal carriage using selective digestive decontamination (SDD); with buccal and oral gentamicin and polymyxin E administration. This will reduce infections and hopefully mortality caused by CRKP.

Conditions

  • Carriage of Carbapemen-resistant Klebsialle Pneumoniae

Interventions

DRUG

Arm #1 :Oral solution and buccal gel of gentamicin and polymyxin E. Arm #2: Placebo.

Arm #1: Oral gentamicin \& polymyxin E, gentamicin \& polymyxin E buccal gel. Arm #2: Oral placebo solutions, placebo buccal gel.

Sponsors & Collaborators

  • Soroka University Medical Center

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-11-30
Primary Completion
2010-06-30
Completion
2010-07-31

Countries

  • Israel

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00753558 on ClinicalTrials.gov