MedTrace Logo

Effects of Administration of Fostamatinib on Blood Concentrations of Digoxin in Healthy Subjects

NCT01355354 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2011-10-06

No results posted yet for this study

Summary

The purpose of this study is to investigate the drug interaction between fostamatinib and digoxin by comparing the safety, tolerability and plasma concentration of digoxin when administered alone and with fostamatinib in healthy subjects.

Conditions

Interventions

DRUG

Digoxin

oral tablets, 0.25mg bd on Day 1 and 0.25 Once daily from Day 2 to 15

DRUG

Fostamatinib

oral tablets, 100mg (2 X 50mg) bd from Day 9 - 15

Sponsors & Collaborators

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-06-30
Primary Completion
2011-09-30
Completion
2011-09-30

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01355354 on ClinicalTrials.gov