MedTrace Logo

Ultrasound-guided Axillary Plexus Block - Dose Reduction of Prilocaine

NCT01309360 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2011-07-12

Study results available
· View outcomes & findings →

Summary

Clinical aim: Does reducing the dose of local anesthetic in ultrasound-guided axillary plexus anesthesia have any effect on the success rate and additional parameters of block quality? Methodology: In this prospective cohort study three groups of 40 outpatients each were administered dosages of 1% prilocaine of either 40mL, 30mL or 20mL for axillary plexus anesthesia. Met-Hb was measured prior to administration of the block and then hourly until the Met-Hb concentration fell. Parameters of block quality and any adverse effects were recorded. The level of significance was defined with α ≤ 0.05.

Conditions

  • Other Surgical Procedures

Interventions

DRUG

midazolam

Prior to performing the regional anesthesia the investigators administered midazolam as a premedication by mouth (3,75-7,5mg) or intravenously (2-3mg).

DRUG

prilocaine 1%

40 outpatients : 40ml prilocaine 1% were administered for axillary plexus block

DRUG

prilocaine 1%

40 outpatients : 30ml prilocaine 1% were administered for axillary plexus block

DRUG

prilocaine 1%

40 outpatients : 20ml prilocaine 1% were administered for axillary plexus block

Sponsors & Collaborators

  • Helios Research Center

    lead OTHER

Principal Investigators

  • Ronald Seidel, Dr. med. · Klinik für Anästhesiologie und Intensivtherapie, Helios Kliniken Schwerin, Wismarsche Strasse 393-7, DE-19049 Schwerin

  • Georg Rehmert, Dr.med. · Klinik für Anästhesiologie und Intensivtherapie, Helios Kliniken Schwerin, Wismarsche Strasse 393-7, DE-19049 Schwerin

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-30
Primary Completion
2010-04-30
Completion
2010-04-30

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01309360 on ClinicalTrials.gov