Azacitidine in Treating Patients With Previously Treated Advanced Non-Small Cell Lung Cancer
NCT01281124 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 1
Last updated 2019-09-24
Summary
This phase II clinical trial is studying how well azacitidine works in treating patients with previously treated advanced non-small cell lung cancer. Drugs used in chemotherapy, such as azacitidine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
Conditions
- Recurrent Lung Non-Small Cell Carcinoma
- Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions
- DRUG
-
Given subcutaneously
- OTHER
-
Diagnostic Laboratory Biomarker Analysis
Correlative studies
- OTHER
-
Pharmacological Study
Correlative studies
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Gregory A Otterson · Ohio State University Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-01-12
- Primary Completion
- 2011-04-15
- Completion
- 2012-09-12
Countries
- United States
Study Locations
More Related Trials
-
Azacitidine and Entinostat in Treating Patients With Newly Diagnosed Stage IA-IIIA Non-Small Lung Cancer Undergoing Surgery
NCT01886573 ·Status: TERMINATED ·Phase: PHASE1
-
FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancer
NCT00020202 ·Status: COMPLETED ·Phase: PHASE2
-
-02341066 and PF-00299804 for Advanced Non-Small Cell Lung Cancer
NCT01441128 ·Status: TERMINATED ·Phase: PHASE1
-
Gemcitabine and Carboplatin With or Without AZD2171 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00326599 ·Status: COMPLETED ·Phase: PHASE2
-
AZD0530 to Treat Recurrent Stage IIIB/IV NSCLC Previously Treated With Combination Chemotherapy
NCT00638937 ·Status: COMPLETED ·Phase: PHASE2
-
Azacitidine and Entinostat in Treating Patients With Stage I Non-Small Cell Lung Cancer That Has Been Removed By Surgery
NCT01207726 ·Status: TERMINATED ·Phase: PHASE2
-
Paclitaxel in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00005646 ·Status: COMPLETED ·Phase: PHASE2
-
Dasatinib in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
NCT00459342 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel and Oxaliplatin in Treating Patients With Recurrent or Advanced Non-small Cell Lung Cancer
NCT00004126 ·Status: COMPLETED ·Phase: PHASE2
-
AZD2171 in Treating Patients With Recurrent Small Cell Lung Cancer
NCT00245063 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Paclitaxel With or Without Vorinostat in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT01413750 ·Status: TERMINATED ·Phase: PHASE2
-
Phase II Trial of a 96-Hour Continuous Infusion of Paclitaxel Followed by Cisplatin for Patients With Stage III/IV and Relapsed NSCLC
NCT00001450 ·Status: COMPLETED ·Phase: PHASE2
-
AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer
NCT02513563 ·Status: COMPLETED ·Phase: PHASE2
-
Paclitaxel in Treating Patients With Recurrent or Refractory Non-small Cell Lung Cancer
NCT00004265 ·Status: UNKNOWN ·Phase: PHASE2
-
Paclitaxel and Irinotecan in Treating Patients With Advanced Non-small Cell Lung Cancer
NCT00004924 ·Status: COMPLETED ·Phase: PHASE2
-
National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer
NCT02664935 ·Status: COMPLETED ·Phase: PHASE2
-
Antineoplaston Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer
NCT00003497 ·Status: TERMINATED ·Phase: PHASE2
-
Ph II Gemcitabine, Erlotinib, and Gemcitabine With Erlotinib/Elderly Patients W/ IIIB/IV NSCLC
NCT00283244 ·Status: COMPLETED ·Phase: PHASE2
-
Carboplatin and Paclitaxel in Treating Older Patients With Metastatic or Recurrent Unresectable Non-small Cell Lung Cancer
NCT00005059 ·Status: COMPLETED ·Phase: PHASE2
-
Platinum-Based Chemotherapy and Durvalumab for the Treatment of Stage IIIB or IV Non-small Cell Lung Cancer
NCT04262869 ·Status: WITHDRAWN ·Phase: PHASE2
-
Dose-Dense Induction/Neoadjuvant Chemotherapy in Locally Advanced Non-Small Cell Lung Cancer
NCT02157116 ·Status: TERMINATED ·Phase: PHASE2
-
AZD0530 in Treating Patients With Extensive Stage Small Cell Lung Cancer
NCT00528645 ·Status: COMPLETED ·Phase: PHASE2
-
Concurrent Proton and Chemotherapy in Locally Advanced Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC)
NCT00495170 ·Status: COMPLETED ·Phase: PHASE2
-
Bryostatin 1 Plus Paclitaxel in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-small Cell Lung Cancer
NCT00005849 ·Status: COMPLETED ·Phase: PHASE2
-
ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer
NCT00662597 ·Status: TERMINATED ·Phase: PHASE3