FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancer
NCT00020202 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2024-03-04
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of FR901228 in treating patients who have refractory or progressive small cell lung cancer or non-small cell lung cancer.
Conditions
- Extensive Stage Small Cell Lung Cancer
- Stage IIIA Non-small Cell Lung Cancer
- Stage IV Non-small Cell Lung Cancer
- Recurrent Small Cell Lung Cancer
- Stage IIIB Non-small Cell Lung Cancer
- Recurrent Non-small Cell Lung Cancer
Interventions
- DRUG
-
FR901228
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
David S. Schrump · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-06-30
- Completion
- 2007-03-31
Countries
- United States
Study Locations
More Related Trials
-
-02341066 and PF-00299804 for Advanced Non-Small Cell Lung Cancer
NCT01441128 ·Status: TERMINATED ·Phase: PHASE1
-
S9914: Combination Chemotherapy Plus Filgrastim in Untreated Extensive-Stage Small Cell Lung Cancer
NCT00004137 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating RO5479599 in Combination With Carboplatin and Paclitaxel in Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC) of Squamous Histology
NCT02204345 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Suramin, Paclitaxel, and Carboplatin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
NCT00006929 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy, Radiation Therapy, and RSR13 in Treating Patients With Stage III Non-small Cell Lung Cancer
NCT00004202 ·Status: COMPLETED ·Phase: PHASE2
-
S0022:Combination Chemotherapy and Radiation Therapy in Treating Patients With Stage IIIB Non-Small Cell Lung Cancer
NCT00014196 ·Status: TERMINATED ·Phase: PHASE2
-
Nitrocamptothecin in Treating Patients With Advanced Small Cell Lung Cancer
NCT00006082 ·Status: COMPLETED ·Phase: PHASE2
-
TLK286 in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT00036920 ·Status: COMPLETED ·Phase: PHASE2
-
Dose-Dense Induction/Neoadjuvant Chemotherapy in Locally Advanced Non-Small Cell Lung Cancer
NCT02157116 ·Status: TERMINATED ·Phase: PHASE2
-
Azacitidine in Treating Patients With Previously Treated Advanced Non-Small Cell Lung Cancer
NCT01281124 ·Status: COMPLETED ·Phase: PHASE2
-
PF-00299804 As A Single Agent, In Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Chemotherapy And Erlotinib
NCT00548093 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Low Dose Chemotherapy Plus Sorafenib as Initial Therapy for Patients With Advanced Non-Squamous Cell NSCLC
NCT00801801 ·Status: TERMINATED ·Phase: PHASE2
-
Karenitecin in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer
NCT00010218 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy and Radiation Therapy in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer That Cannot Be Removed By Surgery
NCT00004253 ·Status: UNKNOWN ·Phase: PHASE2
-
Non-small Cell Lung Cancer Study US75 (Z-PACT)
NCT00086268 ·Status: COMPLETED ·Phase: PHASE3
-
Chemotherapy and Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
NCT00022308 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Buparlisib (BKM120) in Patients With Untreated Squamous Non-small Cell Lung Cancer
NCT01820325 ·Status: TERMINATED ·Phase: PHASE1
-
Specialized Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
NCT01486602 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Evaluating the Efficacy and the Safety of First-line Chemotherapy Combined With the Therapeutic Vaccine Named TG4010 and Nivolumab in Patients With Advanced Non-squamous Non-Small Cell Lung Cancer (NSCLC)
NCT03353675 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib and High-Dose Carboplatin, Paclitaxel, and External-Beam Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer
NCT00547443 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Induction Chemotherapy Using Paclitaxel, Carboplatin, CPT-11 With Pegfilgrastim
NCT00280787 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Followed by Radiation Therapy in Patients With Small Cell Lung Cancer
NCT00002822 ·Status: COMPLETED ·Phase: PHASE3
-
S0119: Combination Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00030433 ·Status: COMPLETED ·Phase: PHASE2
-
Etirinotecan Pegol (NKTR-102) in NSCLC
NCT01773109 ·Status: COMPLETED ·Phase: PHASE2
-
ZD0473 in Treating Patients With Progressive or Relapsed Non-Small Lung Cancer
NCT00021008 ·Status: UNKNOWN ·Phase: PHASE2