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Neuroprotection With Erythromycin in Cardiac Surgery

NCT01274754 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2014-12-03

No results posted yet for this study

Summary

Neurological complications occur in open heart surgery with a frequency of 40% and they range from major neurological deficits (due to a stroke) to neurocognitive and behavioral disorders. This study aims to determine if erythromycin, a worldwide known antibiotic, protects the brain from damage when given in high doses before and during open heart surgery.

The investigators consume that high dose of erythromycin will protect the brain with a pharmacological preconditioning against the global ischemia during the perioperative period of heart surgery.

Conditions

  • Functional Disturbances Following Cardiac Surgery

Sponsors & Collaborators

  • University of Thessaly

    collaborator OTHER

  • AHEPA University Hospital

    lead OTHER

Principal Investigators

  • George Vretzakis, Prof. · University of Thessaly

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-11-30
Primary Completion
2014-07-31
Completion
2014-09-30

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01274754 on ClinicalTrials.gov