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Gene x Behavior Interaction in the Look AHEAD Study

NCT01270763 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 4108

Last updated 2015-03-18

No results posted yet for this study

Summary

The interplay of genetic and behavioral factors is critical to understanding obesity. Behavioral weight loss intervention has emerged as a key strategy in combating obesity. However, individuals differ in their degree of success in these programs and genetic factors are known to play a role. In this application, the investigators propose to identify specific genes that predict individual differences in weight loss and high density lipoprotein cholesterol in response to behavioral intervention to help identify individuals that struggle with weight loss and cholesterol despite behavioral efforts.

Conditions

Interventions

BEHAVIORAL

Intensive lifestyle intervention

Lifestyle intervention focused on weight loss through diet and physical activity

BEHAVIORAL

Diabetes support and education

Behavioral intervention focused on diabetes support and education

Sponsors & Collaborators

  • Tufts Medical Center

    collaborator OTHER

  • Brown University

    collaborator OTHER

  • The Miriam Hospital

    lead OTHER

Principal Investigators

  • Jeanne McCaffery, Ph.D. · The Miriam Hospital

  • Rena Wing, Ph.D. · The Miriam Hospital

Eligibility

Min Age
45 Years
Max Age
74 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-07-31
Primary Completion
2015-03-31
Completion
2015-03-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01270763 on ClinicalTrials.gov