P16 Staining as Prognostic Biomarker in Serous Papillary Endometrial Cancer
NCT01267357 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 62
Last updated 2010-12-28
Summary
P16 is a tumor suppressor protein implicated in serous papillary endometrial carcinoma. Evidence from previous trials indicates that it may be used as a diagnostic biomarker distinguishing this disease from endometrioid endometrial cancer. Additional evidence points to its prognostic value.
The current study will evaluate p16 both as a diagnostic tool for serous papillary endometrial cancer and as a prognostic biomarker.
following anonymization, histology blocks will be microtomed and stained for P16 and P53 proteins.
Blocks from endometrioid endometrial cancer will be used as a control group.
Conditions
- Serous Papillary Endometrial Cancer
Interventions
- OTHER
-
no intervention
Sponsors & Collaborators
-
Rambam Health Care Campus
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-07-31
- Primary Completion
- 2010-11-30
Countries
- Israel
Study Locations
More Related Trials
-
The Effect of Human Placental Explants and Pregnant Women Sera on Cancer Cells
NCT01879436 ·Status: COMPLETED
-
SENTInel Node Mapping Versus Comprehensive Lymphadenectomy in p53-Mutated Endometrial Cancer: A Non-Inferiority Randomized Trial
NCT06900582 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Sentinel Lymph Node Mapping With Different Injection Sites of ICG in Endometrium Cancer
NCT06656949 ·Status: RECRUITING ·Phase: NA
-
Pre-Clinical Models in Gynecological Tumors A Tissue Repository
NCT00250783 ·Status: COMPLETED
-
Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)
NCT06135870 ·Status: RECRUITING
-
Role of Biomarkers in Endometrial Cancer Recurrence in Samples From Patients With Stage II, Stage III, or Stage IV Endometrial Cancer
NCT01150682 ·Status: UNKNOWN
-
Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome
NCT05257057 ·Status: COMPLETED
-
MRI and Metabolomics Biomarkers for Uterine Malignancy
NCT02528864 ·Status: COMPLETED
-
Metastatic Leiomyosarcoma Biomarker Protocol
NCT05653388 ·Status: RECRUITING
-
P53 Immunohistochemistry Abnormal Staining in Endometrial Cancer
NCT05542940 ·Status: COMPLETED
-
Molecular Markers in Treatment in Endometrial Cancer
NCT00598845 ·Status: UNKNOWN
-
Predicting Progression of Developing Myeloma in a High-Risk Screened Population and General Population
NCT05837884 ·Status: RECRUITING
-
Prediction of Recurrence Among Low Risk Endometrial Cancer Patients
NCT04604613 ·Status: ACTIVE_NOT_RECRUITING
-
Molecular and ctDNA Characterization of High-Risk Endometrial Cancer
NCT07062016 ·Status: RECRUITING
-
Relationship of Endometrial Cancer and Serum Soluble L1CAM Level
NCT04603599 ·Status: COMPLETED
-
Reliability and Interest of Circulating Tumor DNA in Endometrial Cancers.
NCT04456972 ·Status: COMPLETED ·Phase: NA
-
Studies of the Tumour Suppressor Gene PTEN - Endometrial Cancer
NCT02724501 ·Status: COMPLETED
-
First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
NCT05627960 ·Status: RECRUITING ·Phase: PHASE1
-
Role of Serum Regucalcin in Diagnosis of Hepatocellular Carcinoma
NCT03206866 ·Status: UNKNOWN
-
Biomarkers and Clinical Features of Metastatic Breast Cancer in Patients Treated With CDK4/6 Inhibitors
NCT04526587 ·Status: RECRUITING
-
The Role of Hypoxia as a Selective Pressure for TP53 Mutations
NCT03466034 ·Status: TERMINATED
-
Estrogen, Diet, Genetics and Endometrial Cancer
NCT00587886 ·Status: ACTIVE_NOT_RECRUITING
-
Genomic Predictors of Papillary Microcarcinoma Disease Progression
NCT02363595 ·Status: RECRUITING
-
Studying Biomarkers in Samples From Patients With Rhabdomyosarcoma
NCT01433237 ·Status: COMPLETED
-
Study of Tumor Samples From Patients With Ewing Sarcoma
NCT00898053 ·Status: COMPLETED