Nerve Growth Factor in Chronic Pancreatitis

NCT01255917 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 38

Last updated 2016-03-07

No results posted yet for this study

Summary

This study is to understand the role of nerve growth factor(NGF) and other cytokines in the pancreatic fluid of patients with chronic pancreatitis.

Hypothesis:

1. Pain does not correlate with changes in the PD morphology suggesting that pain in CP is not only a mechanical problem
2. Pain in CP correlates better with the levels of NGF in the pancreatic juice. NGF is variably expressed in different morphological stages of CP and regulates the sensitivity of the peptidergic nociceptors and is upregulated in pancreatic inflammation.

Conditions

  • Chronic Pancreatitis

Sponsors & Collaborators

Principal Investigators

  • Bimaljit S Sandhu, M.D · Associate Professor, VCU Medical Center

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-02-29
Primary Completion
2011-08-31
Completion
2011-08-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01255917 on ClinicalTrials.gov