Parkinson's Disease, Diagnostic Observations (PADDO)
NCT01249768 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2016-03-31
Summary
Background:
Parkinson's Disease and the Atypical Parkinsonian Disorder (like Multiple System Atrophy, Progressive Supranuclear Palsy, Corticobasal Degeneration, Lewy Body Dementia) are disease entities with partly common symptomatology. Especially very early in the course of disease, the differentiation between both disease entities can be challenging, even for specialists in the field of movement disorder. However, the establishment of a correct diagnosis is very important for adequate patientcounseling, treatment and the correct inclusion of patients in research trials. Ancillary diagnostic investigations are looked upon to aid in this diagnostic dilemma.
Objective:
To investigate the value of ancillary diagnostic investigations, more specific MRI, analysis of cerebrospinal fluids and a second opinion in a specialized movement disorder centre, to differentiate Parkinson's disease and the Atypical Parkisonisonian disorder.
Conditions
- Parkinson's Disease
- Atypical Parkinsonism
Sponsors & Collaborators
-
Radboud University Medical Center
lead OTHER
Principal Investigators
-
M Verbeek, PhD, MSc · Radboud University Medical Center
-
B Bloem, Prof, MD · Radboud University Medical Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-07-31
- Primary Completion
- 2017-07-31
- Completion
- 2018-07-31
Countries
- Netherlands
Study Locations
More Related Trials
-
A Trial of 18F-AV-133 Positron Emission Tomography (PET) Imaging to Differentiate Subjects With Parkinson's Disease (PD) From Other Movement Disorders
NCT01550484 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Assessing Imaging as a Tool in Monitoring and Predicting the Progression of Parkinson Disease
NCT00404170 ·Status: COMPLETED ·Phase: PHASE2
-
The Differential Diagnosis and Prognosis of Idiopathic and Atypical Parkinson Disease by Using Diffusion MRI
NCT04472325 ·Status: COMPLETED
-
Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging
NCT03872102 ·Status: RECRUITING
-
Characterization of Dynamic Stability in Normal Pressure Hydrocephalus and Parkinson's Disease
NCT05998473 ·Status: UNKNOWN
-
Dopamine Turnover Rate as Surrogate Parameter for Diagnosis of Early Parkinson's Disease
NCT00153972 ·Status: COMPLETED ·Phase: PHASE4
-
Study of the Effects of Dopaminergic Medications on Dopamine Transporter Density in Subjects With Parkinson's Disease
NCT00129181 ·Status: COMPLETED ·Phase: NA
-
LIPAD - LRRK2 International Parkinson's Disease Study
NCT04214509 ·Status: UNKNOWN
-
Imaging Neuromelanin and Iron in Dystonia/Parkinsonism
NCT03572114 ·Status: UNKNOWN
-
Evaluating the Effectiveness of Neupro® (Rotigotine) and L-dopa Combination Therapy in Patients With Parkinson's Disease
NCT02227355 ·Status: COMPLETED
-
Asleep MRI-guided Versus Awake Microelectrode Recording Guided Deep Brain Stimulation in Parkinson's Disease: A Comparative Effectiveness Trial
NCT05453331 ·Status: UNKNOWN
-
Common Noradrenergic Mechanisms in Parkinson´s Disease and L-DOPA Induced Dyskinesia
NCT02578849 ·Status: UNKNOWN
-
PharmacoMRI of Parkinson Disease
NCT01528592 ·Status: COMPLETED ·Phase: NA
-
A Study to Assess Changes in Clinical Management After DaTSCAN Imaging of Subjects With Clinically Uncertain Parkinsonism or an Illness With Similar Symptoms
NCT00382967 ·Status: COMPLETED ·Phase: PHASE4
-
Long-Term Dopamine Transporter Imaging and Clinical Assessment of Parkinson's Disease Progression
NCT00134784 ·Status: COMPLETED ·Phase: PHASE2
-
Combined Stimulation of STN and SNr for Resistant Freezing of Gait in Parkinson's Disease
NCT02588144 ·Status: UNKNOWN ·Phase: NA
-
Study of Motor Inhibition in Parkinson's Disease and Focal Hand Dystonia
NCT05209516 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Clinical Decision Support System-mPDia for Neurodegenerative Parkinsonism Using MRI Images
NCT04334902 ·Status: COMPLETED
-
The STEREO-DBS Study: 7-Tesla MRI Brain Network Analysis for Deep Brain Stimulation
NCT05843084 ·Status: RECRUITING
-
DBS Imaging-based vs. Threshold Assessment-based Programming
NCT06223399 ·Status: RECRUITING ·Phase: NA
-
[11C]Donepezil PET For Imaging The Autonomous Nervous System In Parkinsons Disease
NCT02012595 ·Status: COMPLETED
-
Prognostic Values of PET Examination With 11 C-Fe_CIT With Voxel-based Analysis Method in Patients With Sporadic Parkonson's Disease and Parkinsonisms (Prot.PD-diagn).
NCT06171451 ·Status: COMPLETED
-
Superior Cervical Ganglion in Parkinson's Disease
NCT05741151 ·Status: RECRUITING ·Phase: NA
-
Predicting Cognition After DBS for Parkinson's Disease 2
NCT06272968 ·Status: ACTIVE_NOT_RECRUITING
-
Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study
NCT04724941 ·Status: RECRUITING