Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study
NCT04724941 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000
Last updated 2025-09-22
Summary
The PASS-PD study is set out to screen individuals from the general population with an increased risk for the development of Parkinson's Disease (PD) and to investigate this highly enriched cohort longitudinally for five year. A special focus is placed on implementation of ethical standards for early risk disclosure in PD.
Conditions
- Parkinson Disease
Interventions
- OTHER
-
No intervention
No intervention
Sponsors & Collaborators
-
UCB Biopharma SRL
collaborator INDUSTRY -
University of Kiel
collaborator OTHER -
University Hospital Schleswig-Holstein
lead OTHER
Principal Investigators
-
Daniela Berg, Prof.Dr. · Department for Neurology, University of Kiel
Eligibility
- Min Age
- 50 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2021-06-01
- Primary Completion
- 2027-12-31
- Completion
- 2027-12-31
Countries
- Germany
Study Locations
More Related Trials
-
FDOPA PET and Nutritional Support in Parkinson's Disease
NCT04459052 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Parkinson's Disease, Diagnostic Observations (PADDO)
NCT01249768 ·Status: UNKNOWN
-
Study of Motor Inhibition in Parkinson's Disease and Focal Hand Dystonia
NCT05209516 ·Status: UNKNOWN ·Phase: NA
-
Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease. Extension to HP-CD-CL-2002 Clinical Study
NCT03775538 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease
NCT07227896 ·Status: NOT_YET_RECRUITING
-
Study to Assess Real Life Effectiveness of Foslevodopa/Foscarbidopa in Adult German Participants at Initial Stages of Advanced Parkinson's Disease (EARLY-FOS)
NCT06916507 ·Status: RECRUITING
-
Multi-centre UK Study of the Acetylcholinesterase Inhibitor Donepezil in Early Dementia Associated With Parkinson's Disease
NCT01014858 ·Status: TERMINATED ·Phase: PHASE3
-
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment
NCT00306124 ·Status: UNKNOWN ·Phase: PHASE4
-
Super-resolution of Brain Magnetic Resonance Images in Deep Brain Stimulation for Parkinson's Disease
NCT05596201 ·Status: COMPLETED
-
Prospective Study to Compare Results of STN-DBS Between Early Treated and Late-treated PD Patient
NCT01274832 ·Status: UNKNOWN
-
Combined Stimulation of STN and SNr for Resistant Freezing of Gait in Parkinson's Disease
NCT02588144 ·Status: UNKNOWN ·Phase: NA
-
Evaluating the Effectiveness of Neupro® (Rotigotine) and L-dopa Combination Therapy in Patients With Parkinson's Disease
NCT02227355 ·Status: COMPLETED
-
Multicenter Study of Blood Biomarkers of Mitochondrial and Peroxisomal Metabolism to Differentiate Idiopathic Parkinson's Disease From Related Conditions
NCT05110547 ·Status: UNKNOWN
-
Long Term Follow-up of Patients With Parkinson's Disease Who Had Administered of A9-DPC in SB-PD-001 Study
NCT06477744 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Safety and Tolerability Study Evaluating ACR325 in Parkinson's Disease Patients
NCT01023282 ·Status: COMPLETED ·Phase: PHASE1
-
Parkinsonian Patients Treated With Apomorphine Pump: Observatory of Skin Lesions
NCT05331573 ·Status: UNKNOWN
-
Directional Deep Brain Stimulation With Patients With Advanced Parkinson's Disease
NCT05394688 ·Status: COMPLETED
-
Asleep MRI-guided Versus Awake Microelectrode Recording Guided Deep Brain Stimulation in Parkinson's Disease: A Comparative Effectiveness Trial
NCT05453331 ·Status: UNKNOWN
-
AI-based Progression and Medication Response Prediction Study in Parkinson's Disease
NCT07189468 ·Status: NOT_YET_RECRUITING
-
Study on Practical ExperienceS of Treatment With Foslevodopa/foScaRbidopa in Advanced Parkinson's Disease
NCT06937034 ·Status: RECRUITING
-
Dopamine Turnover Rate as Surrogate Parameter for Diagnosis of Early Parkinson's Disease
NCT00153972 ·Status: COMPLETED ·Phase: PHASE4
-
Systematic Follow up of Second Line Treatments for Parkinson's Disease (Deep Brain Stimulation, Apomorphin Pump, Duodopa Pump)
NCT05072015 ·Status: NOT_YET_RECRUITING
-
Study of the Effects of Dopaminergic Medications on Dopamine Transporter Density in Subjects With Parkinson's Disease
NCT00129181 ·Status: COMPLETED ·Phase: NA
-
Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism
NCT01358474 ·Status: COMPLETED
-
Evolution of Hypodopaminergic Syndrome in Early Parkinson's Disease
NCT03141944 ·Status: COMPLETED