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Effect on Acetaminophen Metabolism by Liquid Formulations

NCT01246713 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2017-05-08

Study results available
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Summary

The purpose of this study is to determine whether excipients in the liquid formulation of acetaminophen prevent the formation of the toxic metabolites of acetaminophen.

Conditions

  • Acetaminophen Metabolism
  • Acetaminophen Poisoning
  • Drug Metabolism by Excipients

Interventions

DRUG

Acetaminophen liquid formulation

Subjects in this arm will receive a 15mg/kg dose of a solid acetaminophen formulation.

DRUG

Acetaminophen solid formulation

Subjects in this arm will receive a 15mg/kg dose of a solid acetaminophen formulation.

Sponsors & Collaborators

Principal Investigators

  • Michael Ganetsky, MD · Beth Israel Deaconess Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-12-31
Primary Completion
2011-05-31
Completion
2012-07-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01246713 on ClinicalTrials.gov