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Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever

NCT01137591 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2015-03-05

No results posted yet for this study

Summary

The purpose of this study is to compare the efficacy of the an N-acetyl-p-aminophenol (APAP, also known as acetaminophen) and N-acetylcysteine (NAC) combination versus an APAP-placebo combination as an anti-pyretic agent.

Conditions

  • Liver Failure
  • Liver Failure, Acute
  • Drug Induced Liver Injury
  • Prevention & Control
  • Fever

Interventions

DRUG

APAP and NAC combination

APAP 650mg and NAC 600mg combination oral tablet administered once

DRUG

APAP and Placebo

APAP 650mg and Placebo combination oral tablet administered once

Sponsors & Collaborators

Principal Investigators

  • Matthew Chang, MD · Columbia University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-04-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01137591 on ClinicalTrials.gov