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Single Oral Dose of Dexamethasone Versus Five Days of Prednisone in Adult Asthma

NCT01241006 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 376

Last updated 2016-01-07

No results posted yet for this study

Summary

This study seeks to compare the effectiveness of a single dose of oral dexamethasone versus 5 days of oral prednisone in the treatment of mild to moderate asthma exacerbations to prevent relapse with an unscheduled return visit to a health care provider for additional asthma treatment within 14 days. The investigators hypothesize that the two treatments will be equally effective in relapse prevention.

Conditions

  • Asthma
  • Reactive Airway Disease

Interventions

DRUG

Dexamethasone

Dexamethasone 12mg PO single dose x 1 Placebo 1 capsule PO for 4 days

DRUG

Prednisone

Prednisone 60mg PO q day for 5 days

Sponsors & Collaborators

  • Alameda County Medical Center

    lead OTHER

Principal Investigators

  • Barry Simon, MD · Alameda County Medica Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-01-31
Primary Completion
2015-05-31
Completion
2015-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01241006 on ClinicalTrials.gov