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Nicotine and Brain Imaging Research Study

NCT01227343 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 54

Last updated 2021-08-04

No results posted yet for this study

Summary

The aim of this study is to assess the impact of smoking on cortical GABA levels in males and females. Using magnetic resonance spectroscopy (MRS), we will examine the impact of sex and menstrual cycle phase on brain neurochemistry in healthy smokers and non-smokers. We hypothesize that female, but not male, smokers will have reduced cortical GABA levels compared to their non-smoking, sex-matched counterparts.

Conditions

  • Nicotine

Sponsors & Collaborators

Principal Investigators

  • Cynthia N Epperson, M.D. · University of Pennsylvania

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-03-31
Primary Completion
2016-11-30
Completion
2017-11-30

Countries

  • United States

Study Locations

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Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01227343 on ClinicalTrials.gov