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MRA/fMRI Study of Spontaneous Migraine

NCT01471314 · Status: UNKNOWN · Type: OBSERVATIONAL

Last updated 2012-08-29

No results posted yet for this study

Summary

The purpose of this study is to examine migraineurs during spontaneous migraine attacks without aura, using high resolution magnetic resonance imaging (MRI), to study following:

* Changes in resting state blood-oxygenation-level-dependent-signal (BOLD-signal) using functional MRI (fMRI).
* Changes in circumferences of intra- and extracranial arteries using MR-angiography (MRA).
* Changes in regional and global cerebral blood flow (CBF) using the arterial spin labeling (ASL) method.

Moreover to perform diffusion tensor imaging (DTI) scans during spontaneous migraine attacks.

The migraine specific drug sumatriptan will be given to relieve pain and the effect will be registered using MRA and fMRI if possible.

Conditions

  • Headache Versus Non-headache Day

Interventions

BEHAVIORAL

Headache day versus non-headache day

Sponsors & Collaborators

  • Leiden University Medical Center

    collaborator OTHER

  • Glostrup University Hospital, Copenhagen

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01471314 on ClinicalTrials.gov