Modelling of Energy Expenditure From Heart Rate, Accelerometry and Other Physiological Parameters

Summary

At this time, 24h energy expenditure is rarely assessed under free-living conditions for specific individuals because of the lack of cheap and accurate software/materials to record the energy expenditure. Some affordable and convenient tools (Polar heart rate monitor, Actiheart, SenseWear Armband) are available on the market but the predictive equations comprised into the software provided with these tools generally miscalculate the energy expenditure (by about +/-10%). Because of this deficiency, the investigators have a poor knowledge of the modification of the energy expended during daily life activities and over 24h in subjects belonging to groups of various ages and physiological states. The investigators hypothesise that it could be possible to improve the energy expenditure prediction.

The project aims at providing a mathematical model (equations) that predicts energy expenditure with an error near to 5%. Two groups of 60 sedentary to athletic normal weight volunteers aged between 18-60 years participate to this study. The first group stay for 26h in calorimetric chambers. During this stay energy expenditure ,heart rate, accelerometry, and other parameters are recorded during various activities. These data will serve to construct the model. The same type of recordings are performed on second group of volunteers in free living conditions. Their energy expenditure is measured overall by doubly labeled water. The data of the second group will serve to validate the model. The error percentage of the model is defined by the ratio of the value of the difference between prediction and reference measure to the reference measure. Concordance between predictions and measures will be evaluated by Bland - Altman plots.

Conditions

• Computer Simulation
• Energy Expenditure
• Energy Metabolism

Interventions

DEVICE

calorimetric chamber

Participants stayed 26h in a calorimetric chamber. They performed a series of physical activities such as walking on a treadmill at different speeds, writing, standing, standing-sitting, stepper , rest , sleeping and eating. They also performed a power test on an ergocycle at different speeds.

DEVICE

Free living conditions

Volunteers followed the protocol of doubly labeled water to evaluate their energy expenditure during 10 days in free living conditions. For this period, their heart rate, parameters of actimetry and other parameters were recorded.

Sponsors & Collaborators

• Centre de Recherche en Nutrition Humaine d'Auvergne

  collaborator OTHER_GOV

• Centre de Recherche en Nutrition Humaine Rhone-Alpe

  collaborator OTHER

• Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

  lead OTHER

Principal Investigators

• Yves Boirie, MD-PhD · Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

60 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2009-01-31

Primary Completion

2009-11-30

Completion

2010-09-30

Countries

• France

Study Locations