GDF 15 in Sickle Cell Disease and Hereditary Spherocytosis
NCT01201135 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 80
Last updated 2010-09-14
Summary
Patients with thalassemia intermedia, congenital dyserythropoietic anemia type I , and sideroblastic anemia were found to express very high levels of serum GDF15, and this contributed to the inappropriate suppression of hepcidin with subsequent secondary iron overload.The aim of our present study is to asses the levels of GDF15 and hepcidin in patients with Sickle cell disease and hereditary spherocytosis
Conditions
- Patients With Thalassemia Intermedia,
- Congenital Dyserythropoietic Anemia Type I
Sponsors & Collaborators
-
Wolfson Medical Center
lead OTHER_GOV
Principal Investigators
-
GHOTI HOSSAM, doctor · HEMATOLOGY DEPARTMENT ON WOLFSSON MEDICAL CENTER
Eligibility
- Min Age
- 5 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-09-30
- Primary Completion
- 2011-09-30
- Completion
- 2011-09-30
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