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NADPH Oxidase Polymorphisms in Obstructive Sleep Apnea Syndrome (OSAS)

NCT01141829 · Status: UNKNOWN · Type: OBSERVATIONAL

Last updated 2010-06-11

No results posted yet for this study

Summary

Obstructive Sleep Apnea (OSA) is associated with increased oxidative stress. The major sources of Reactive Oxygen Species (ROS) in the vasculature are the NADPH oxidases. Several polymorphisms related to NADPH oxidase expression or NADPH oxidase activity has been identified. The investigators are going to compare the distribution of the allelic frequencies of A-930G and C242T polymorphisms and their possible relationship with the levels of 8-isoprostanes as a marker of oxidative stress in patients with OSA and in a control group without OSA.

Conditions

  • Sleep Apnea Syndrome
  • Oxidative Stress
  • Single Nucleotide Polymorphism

Sponsors & Collaborators

  • Spanish Research Center for Respiratory Diseases

    collaborator OTHER

  • Sociedad Española de Neumología y Cirugía Torácica

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01141829 on ClinicalTrials.gov