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Childhood Cancer Survivor Study

NCT01120353 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50000

Last updated 2026-04-24

No results posted yet for this study

Summary

The Childhood Cancer Survivor Study (CCSS) will investigate the long-term effects of cancer and its associated therapies. A retrospective cohort study will be conducted through a multi-institutional collaboration, which will involve the identification and active follow-up of a cohort of approximately 50,000 survivors of cancer, diagnosed before 21 years of age, between 1970 and 1999 and 10,000 sibling controls. This project will study children and young adults exposed to specific therapeutic modalities, including radiation, chemotherapy, and/or surgery, who are at increased risk of late-occurring adverse health outcomes. A group of sibling controls will be identified and data collected for comparison purposes.

Conditions

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Fred Hutchinson Cancer Center

    collaborator OTHER

  • Nationwide Children's Hospital

    collaborator OTHER

  • M.D. Anderson Cancer Center

    collaborator OTHER

  • University of Southern California

    collaborator OTHER

  • Children's Hospital Medical Center, Cincinnati

    collaborator OTHER

  • University of California, San Francisco

    collaborator OTHER

  • St. Jude Children's Research Hospital

    lead OTHER

Principal Investigators

  • Gregory T. Armstrong, MD, MSCE · St. Jude Children's Research Hospital

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1995-01-05
Primary Completion
2026-11-30
Completion
2026-11-30

Countries

  • United States
  • Canada

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01120353 on ClinicalTrials.gov