Italian Validation of the Revised MDS-Unified Parkinson's Disease Rating Scale

Summary

The present study is part of an international program and deals with the translation and validation program for the Italian version of the MDS-UPDRS.

The program will be articulated in three steps:

* Phase I: translation and back-translation of the MDS-UPDRS in Italian (completed)
* Phase II: Cognitive testing. This step is aimed at a preliminary testing of a subset of potentially culturally sensitive items in a limited set of PD patients (approximately 10). Should this phase identify issues in the understanding and ease of use of some items a revised translation of some individual items might be envisaged.
* Phase III: large validation testing: this phase will involve 350 PD patients from 12-14 Italian PD centres.

The IRIS protocol deals with phase II and III of the program.

Conditions

• Parkinson's Disease

Interventions

OTHER

Rating Scale administration

Movement Disorder Society\_Unified Parkinson's Disease Rating Scale will be submitted to the patient (with the help of the caregiver) in a single visit lasting about 40 minutes.

Sponsors & Collaborators

• Fondazione Neureca

  lead OTHER

Principal Investigators

• Paolo Barone, Prof. · Universita' Federico II di Napoli

• Maurizio Zibetti, Dr · Azienda Sanitaria Ospedaliera "San Giovanni Battista di Torino" Le Molinette

• Angelo Antonini, Prof · Ospedale San Camillo IRCCS Venezia

• Gianni Pezzoli, Prof · Istituti Clinici di Perfezionamento Milano

• Michele Tinazzi, Prof · Azienda Ospedaliera Universitaria Integrata Verona - Policlinico G.Rossi

• Giovanni Abbruzzese, Prof · Universita' di Genova

• Ubaldo Bonuccelli, Prof · Universita' di Pisa

• Giovanni Fabbrini, Dr · Universita' La Sapienza di Roma

• Letterio Morgante, Prof · Azienda Ospedaliera Universitaria Policlinico G.Martino di Messina

• Mario Zappia, Prof · Azienda Ospedaliero-Universitaria Policlinico Vittorio Emanuele di Catania

• Alberto Albanese, Prof · Istituto Neurologico Carlo Besta di Milano

• Claudio Pacchetti · Istituto Neurologico Nazionale Fondazione IRCCS "C. Mondino" di Pavia

• Aldo Quattrone, Prof · Policlinico Universitario Mater Domini di Catanzaro

• Giovanni Cossu, Dr · Azienda Ospedaliera "G. Brotzu" di Cagliari

• Aroldo Rossi, Prof · Universita' degli Studi di Perugia

• Paolo Martinelli, Prof · Universita' di Bologna

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2010-03-31

Primary Completion

2010-12-31

Completion

2010-12-31

Countries

• Italy

Study Locations