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REducing SPEECH-related Side-effects of Deep Brain Stimulation in Parkinson's Disease Via Automated Speech Analysis

NCT05182892 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2025-04-09

No results posted yet for this study

Summary

The investigators' objective is to improve L-dopa sensitive PD-related dysarthria and at the same time reduce DBS-induced speech disorders with the help of automated acoustic analysis in patients with STN-DBS-induced dysarthria.

Conditions

  • Parkinson Disease

Interventions

OTHER

Change of stimulation amplitudes in dopaminergic OFF drug state

Change of stimulation amplitudes during experiment in dopaminergic OFF drug state.

Sponsors & Collaborators

  • Czech Technical University in Prague

    collaborator OTHER

  • Insel Gruppe AG, University Hospital Bern

    lead OTHER

Principal Investigators

  • Paul Krack, Prof. · Insel Gruppe AG, University Hospital Bern

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-13
Primary Completion
2025-11-30
Completion
2026-02-28

Countries

  • Czechia
  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05182892 on ClinicalTrials.gov