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Predicting Cognition After DBS for Parkinson's Disease

NCT03982953 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2021-05-07

No results posted yet for this study

Summary

The aim of the study is to improve estimation of cognitive outcome after STN-DBS in PD in order to

* avoid risk factors by optimizing peri- and intraoperative management
* personalize therapeutic strategies for optimal long-term benefit

The investigators will test possible predictors (clinical, neuropsychological, neuroimaging, electrophysiological and molecular) for the risk of cognitive dysfunction after deep brain stimulation of the subthalamic nucleus (STN-DBS) in Parkinson's disease (PD) at a single center (Charité - Universitätsmedizin Berlin, Germany). Data collection takes place prior to as well as 3 and 12 months after the STN-DBS operation. Participation is proposed to all PD patients that are planned to undergo STN-DBS after careful examination of eligibility for this treatment according to standard operation procedures.

Conditions

  • Parkinson's Disease
  • Deep Brain Stimulation
  • Postoperativeneurocognitive Deficit
  • Postoperative Delirium

Sponsors & Collaborators

  • Charite University, Berlin, Germany

    lead OTHER

Principal Investigators

  • Andrea A Kühn, Prof. MD · Neurology, Head of the Movement Disorders and Neuromodulation Section

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-06-12
Primary Completion
2022-06-10
Completion
2022-08-10

Countries

  • Germany

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03982953 on ClinicalTrials.gov