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Portal Venous Hemodynamic Changes After Hepatectomy

NCT01073345 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 110

Last updated 2010-02-23

No results posted yet for this study

Summary

The aim of this study is to investigate the pathophysiological mechanisms underlying the formation of posthepatectomy ascites with a focus on the significance of changes in portal venous hemodynamics after hepatic resection. By evaluation of other factors that may be involved in the formation of ascites this study may help to show to what extent the increase of portal venous pressure contributes to ascites formation. Detailed knowledge about pathogenetic factors concerning the formation of postoperative ascites might help preventing protracted hospital stay and further inconveniences to the patient.

Conditions

  • Ascites
  • Hepatectomy

Interventions

PROCEDURE

Portal venous pressure

Portal venous pressure is measured by invasive means using an arterial canula

PROCEDURE

Portal venous flow

Portal venous flow is measures using a noninvasive method (Doppler flow meter)

PROCEDURE

Hepatic artery flow

Hepatic artery flow will be measured using a noninvasive method (Doppler flow meter)

Sponsors & Collaborators

  • Heidelberg University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-02-28
Primary Completion
2010-12-31
Completion
2010-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01073345 on ClinicalTrials.gov