Study of a Screening Blood Test to Determine Patients' Potential Risk of Adenomatous or Advanced Colon Polyps (ACPs)
NCT01062035 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 72
Last updated 2014-06-26
Summary
The aim of this study is to develop a blood test to determine which patients are at risk for pre-cancerous colon polyps (ACPs: Advanced Colon Polyps). The telomere length of peripheral blood lymphocytes (PBLs) can be measured from a blood sample. Mechanistic pathways and the investigator's preliminary data support PBL telomere length as a biomarker for ACPs. The long-term goal of this project is to decrease deaths from colon cancer by using a blood test to target colonoscopy for those patients who are at high risk for pre-cancerous polyps.
Conditions
- Colonic Polyp
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Douglas L Riegert-Johnson, M.D. · Mayo Clinic
Eligibility
- Min Age
- 50 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-01-31
- Primary Completion
- 2013-09-30
- Completion
- 2013-09-30
Countries
- United States
Study Locations
More Related Trials
-
Fludeoxyglucose F 18 PET Imaging in Determining Protein and Gene Expression Signatures in Patients With Premalignant Polyps or Colon Cancer
NCT00550628 ·Status: COMPLETED
-
Prevalence and Spectrum of Cancer Susceptibility Among Patients with Advanced Colorectal Polyps
NCT04160832 ·Status: COMPLETED
-
Colonoscopic Removal of Aberrant Crypt Foci: a Prospective, Randomized, Blinded Trial
NCT00623883 ·Status: COMPLETED ·Phase: NA
-
Extracolonic Findings on Computed Tomography (CT) Colonography
NCT01465425 ·Status: UNKNOWN
-
Plasma ctDNA in Patients Undergoing Diagnostic Colonoscopy
NCT02665299 ·Status: COMPLETED
-
Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal Cancer Undergoing Chemotherapy
NCT01934179 ·Status: TERMINATED
-
Prevention of Colorectal Cancer Through Multiomics Blood Testing
NCT04369053 ·Status: COMPLETED
-
Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
NCT05410977 ·Status: RECRUITING
-
National Colorectal Polyp Care
NCT03712059 ·Status: COMPLETED
-
Validation of Advanced Colorectal Neoplasm Risk Categories in a Prospective Cohort in Mexico
NCT05661292 ·Status: UNKNOWN
-
Multi-marker Stool Test for Detection of Colorectal Neoplasia: Marker Panel Selection and Technical Development Studies
NCT01260168 ·Status: COMPLETED
-
Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation Assay
NCT00696345 ·Status: COMPLETED
-
Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas
NCT00843375 ·Status: RECRUITING
-
Unprepped CT Colonography
NCT00586053 ·Status: COMPLETED
-
Screening and Risk Factors of Colon Neoplasia
NCT01647776 ·Status: COMPLETED
-
Retroflexion in the Entire Colon for the Detection of Colon-related Diseases
NCT03735953 ·Status: UNKNOWN ·Phase: NA
-
Plasma-based Colorectal Cancer Screening Research & Development
NCT04027790 ·Status: COMPLETED
-
Study of Biomarkers in Blood & Tissue Samples From Patients With Colorectal Cancer or Polyps & Patients Without Polyps
NCT00898378 ·Status: COMPLETED
-
Evaluation of Computer-assisted, Non-cathartic CT Colonography
NCT01200303 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study
NCT05994482 ·Status: RECRUITING
-
De-implementation of Outdated Colonoscopy Surveillance Interval Recommendations Among Patients With Low-risk Adenomas
NCT05389397 ·Status: COMPLETED ·Phase: NA
-
Hereditary Colorectal and Associated Tumor Registry Study
NCT00633607 ·Status: COMPLETED
-
Molecular Stethoscope
NCT02578264 ·Status: COMPLETED
-
Metagenomic Evaluation of the Gut Microbiome in Patients With Lynch Syndrome and Other Hereditary Colonic Polyposis Syndromes
NCT02371135 ·Status: ACTIVE_NOT_RECRUITING
-
Collecting Recorded Videos of Colonoscopy Tests
NCT03937063 ·Status: COMPLETED