Study of Biomarkers in Blood & Tissue Samples From Patients With Colorectal Cancer or Polyps & Patients Without Polyps
NCT00898378 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 551
Last updated 2014-09-18
Summary
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer, patients with colorectal polyps and from patients without polyps may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research study is looking at biomarkers in blood and tissue samples from patients with colorectal cancer or colorectal polyps and from patients without polyps (healthy volunteers).
Conditions
- Colorectal Cancer
- Healthy, no Evidence of Disease
- Precancerous Condition
Interventions
- GENETIC
-
gene expression analysis
gene expression analysis
- GENETIC
-
polymerase chain reaction
polymerase chain reaction
- GENETIC
-
polymorphism analysis
polymorphism analysis
- GENETIC
-
protein expression analysis
protein expression analysis
- GENETIC
-
proteomic profiling
proteomic profiling
- OTHER
-
gas chromatography
gas chromatography
- OTHER
-
laboratory biomarker analysis
laboratory biomarker analysis
- OTHER
-
liquid chromatography
liquid chromatography
- OTHER
-
mass spectrometry
mass spectrometry
- OTHER
-
questionnaire administration
questionnaire administration
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Indiana University
lead OTHER
Principal Investigators
-
Patrick J Loehrer, MD · Indiana University Melvin and Bren Simon Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-01-31
- Primary Completion
- 2014-03-31
- Completion
- 2014-03-31
Countries
- United States
Study Locations
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