Fludeoxyglucose F 18 PET Imaging in Determining Protein and Gene Expression Signatures in Patients With Premalignant Polyps or Colon Cancer
NCT00550628 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 8
Last updated 2015-12-23
Summary
RATIONALE: Diagnostic imaging procedures, such as fludeoxyglucose F 18 PET, may be effective in detecting cancer or recurrence of cancer, or premalignant polyps.
PURPOSE: This clinical trial is studying fludeoxyglucose F 18-PET imaging to see how well it works in determining protein and gene expression signatures in patients with premalignant polyps or colon cancer.
Conditions
- Colorectal Cancer
- Neoplasm of Uncertain Malignant Potential
Interventions
- GENETIC
-
DNA methylation analysis
- GENETIC
-
fluorescence in situ hybridization
- GENETIC
-
gene expression analysis
- GENETIC
-
polymerase chain reaction
- GENETIC
-
protein expression analysis
- GENETIC
-
reverse transcriptase-polymerase chain reaction
- OTHER
-
diagnostic laboratory biomarker analysis
- OTHER
-
immunoenzyme technique
- OTHER
-
immunohistochemistry staining method
- PROCEDURE
-
biopsy
- PROCEDURE
-
therapeutic conventional surgery
- RADIATION
-
fludeoxyglucose F 18
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Marc J. Gollub, MD · Memorial Sloan Kettering Cancer Center
-
Suresh Jhanwar, PhD · Memorial Sloan Kettering Cancer Center
Eligibility
- Min Age
- 15 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-09-30
- Primary Completion
- 2011-09-30
- Completion
- 2011-09-30
Countries
- United States
Study Locations
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