Epigenetic Regulation of BDNF in Schizophrenia
NCT01021449 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 129
Last updated 2013-09-12
Summary
In this proposal, we will (1) detect the associations between BDNF and Trk B gene DNA methylation, histone modification, psychotic symptoms, obesity, suicide and antipsychotic drug responses in Taiwanese patients (2) discuss the possible mechanisms of epigenetic regulation of BDNF and Trk B in schizophrenia patients.
Conditions
- BDNF, DNA Methylation, Suicide, Drug Responses.
Sponsors & Collaborators
-
Chang Gung Memorial Hospital
lead OTHER
Principal Investigators
-
Tiao-Lai Huang, M.D. · Chang-Gung Memorial Hospital, Kaohsiung
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-12-31
- Primary Completion
- 2010-11-30
- Completion
- 2010-11-30
Countries
- Taiwan
Study Locations
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