Quetiapine Related Neurochemical Changes as Measured by Magnetic Resonance Spectroscopy in Schizophrenia
NCT00797927 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2009-04-29
Summary
we aim to examine whether a representative atypical antipsychotic, quetiapine, has different effects from conventional antipsychotics on the magnetic resonance spectroscopy (MRS) markers in schizophrenia patients.
Conditions
Interventions
- DRUG
-
quetiapine
quetiapine (with equivalent dose to original antipsychotic agent) would replace the original antipsychotic agent for 28 days
- OTHER
-
no intervention
keep the original conventional antipsychotic agent for 28 days
Sponsors & Collaborators
-
National Science and Technology Council, Taiwan
collaborator OTHER_GOV -
National Taiwan University Hospital
lead OTHER
Principal Investigators
-
Tzung-Jeng Hwang, MD · Department of Psychiatry, National Taiwan University Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-01-31
- Primary Completion
- 2009-03-31
- Completion
- 2009-04-30
Countries
- Taiwan
Study Locations
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