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Recording and Modulation of Neuronal Mechanisms During Operant Conditioning: a MEG Study

NCT01006109 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2019-12-17

No results posted yet for this study

Summary

Background:

\- Most of the time, humans make decisions according to their consequences, especially if they will be beneficial, and will avoid or try to avoid doing an action if it has a bad outcome. The way that the brain prepares a movement has been studied in detail, but the way the brain makes decisions before carrying out an action is still poorly understood. Researchers are interested in learning more about the decision-making process and how it affects the brain.

Objectives:

\- To record the activity of the brain during decision-making processes.

Eligibility:

\- Healthy, right-handed volunteers between 18 and 40 years of age.

Design:

* Potential participants will have a screening visit with a medical history and neurological examination to determine eligibility.
* This study requires seven visits: one magnetic resonance imaging (MRI) visit and 6 magnetoencephalography (MEG) recording visits. The MEG recording visits will include transcranial magnetic stimulation (TMS). All visits will be spaced at least 1 week apart. Total participation will last about 6 weeks.
* Participants will have an MRI scan at the first study visit.
* The MEG procedures will record brain activity during a series of computer tests involving winning or losing money. TMS will be performed during these visits, separate from the test....

Conditions

Sponsors & Collaborators

  • National Institute of Neurological Disorders and Stroke (NINDS)

    lead NIH

Principal Investigators

  • Mark Hallett, M.D. · National Institute of Neurological Disorders and Stroke (NINDS)

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-10-22
Completion
2017-09-07

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01006109 on ClinicalTrials.gov