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Macrolide Maintenance Therapy in Chronic Obstructive Pulmonary Disease

NCT00985244 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 92

Last updated 2013-06-26

No results posted yet for this study

Summary

To assess whether maintenance treatment with macrolide antibiotics in COPD patients with three or more exacerbations in the preceding year of inclusion can decrease the exacerbation rate in the year of treatment.

Conditions

Interventions

DRUG

Azithromycin

Subjects in this group will receive 3 times a week 500 mg of the antibiotic azithromycin during 1 year.

DRUG

Placebo

Persons in this group will receive 3 times a week placebo of azithromycin during 1 year.

Sponsors & Collaborators

  • Erasmus Medical Center

    collaborator OTHER

  • Stichting Solong

    collaborator UNKNOWN

  • Amphia Hospital

    collaborator OTHER

  • R.S. Djamin

    lead OTHER

Principal Investigators

  • Joachim Aerts, MD, PhD · Amphia ziekenhuis

  • Menno van der Eerdem, MD, PhD · Erasmus Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-05-31
Primary Completion
2013-06-30
Completion
2013-06-30

Countries

  • Netherlands

Study Locations

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Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00985244 on ClinicalTrials.gov