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Selection of Antibiotic Resistance by Azithromycin and Clarithromycin in the Oral Flora

NCT00354952 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 203

Last updated 2006-07-20

No results posted yet for this study

Summary

Resistance to antibiotics is a major public-health problem and studies linking antibiotic use and resistance have shown an association not a causal effect. Utilizing the newer macrolides, azithromycin and clarithromycin that are commonly prescribed for respiratory infections, we investigated the direct impact of antibiotic exposure on resistance at the individual level.

Conditions

  • Healthy Volunteers

Interventions

DRUG

Macrolides (azithromycin or clarithromycin)

Sponsors & Collaborators

  • Abbott

    collaborator INDUSTRY

  • Universiteit Antwerpen

    lead OTHER

Principal Investigators

  • Herman Goossens, MD, PhD · Universiteit Antwerpen

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
DOUBLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2002-07-31
Completion
2003-10-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00354952 on ClinicalTrials.gov