Early Recognition of Pulmonary Arterial Hypertension in Myelodysplastic and Myeloproliferative Diseases
NCT00909467 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 86
Last updated 2012-03-09
Summary
Myelodysplastic and myeloproliferative Disease represent conditions with increased risk for pulmonary hypertension. However, the exact prevalence of pulmonary hypertension in these conditions is not known. The effects of pulmonary hypertension on the clinical picture and the symptoms of patients in these conditions needs also further exploration. This exploratory study is designed to describe the prevalence of pulmonary hypertension in the population with such hematologic diseases, and the stages of pulmonary hypertension as well its effect on exercise capacity at time of diagnosis.
Conditions
- Myeloproliferative Disorder
- Myelodysplastic Syndromes
- Pulmonary Hypertension
Interventions
- OTHER
-
echocardiography, right heart catheterisation
at each patient an echocardiography will be performed at rest and during exercise. For the evaluation of exercise capacity, cardiopulmonary exercise testing and six-minute walk is performed. Right heart catheterisation is recommended to those with suspected pulmonary hypertension.
Sponsors & Collaborators
-
Medical University of Graz
lead OTHER
Principal Investigators
-
Horst Olschewski, MD · Medical University of Graz, Pulmonology
Eligibility
- Min Age
- 18 Years
- Max Age
- 95 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-04-30
- Primary Completion
- 2011-11-30
- Completion
- 2011-11-30
Countries
- Austria
Study Locations
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