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Protein and RNA Expression Patterns in Predicting Response to Treatment in Patients With Lung Cancer

NCT00897650 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 204

Last updated 2017-07-19

No results posted yet for this study

Summary

RATIONALE: Studying samples of tumor tissue and blood in the laboratory from patients with cancer may help doctors learn more about changes that occur in genetic material (DNA and RNA) and may also identify protein expression patterns related to cancer. It may also help doctors predict how patients will respond to treatment.

PURPOSE: This research study evaluates changes in DNA, RNA, and proteins with the goal of predicting response to treatment in patients with lung cancer.

Conditions

Interventions

GENETIC

DNA/RNA sequencing and expression levels

Lung tumor tissue will be collected.

GENETIC

Protein expression analysis

Lung tumor tissue will be collected.

PROCEDURE

Lung tumor biopsy

Tissue will be collected by percutaneous fine needle aspiration, a percutaneous core biopsy, or during a medically indicated procedure during which lung tumor tissue will be removed

PROCEDURE

Blood sample

Patients will be asked for a venous blood sample

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Vanderbilt-Ingram Cancer Center

    lead OTHER

Principal Investigators

  • Christine Lovly, MD, PhD · Vanderbilt-Ingram Cancer Center

Eligibility

Max Age
120 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-12-31
Primary Completion
2016-07-31
Completion
2017-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00897650 on ClinicalTrials.gov