Developing Mouse Models of Breast Cancer Using Tissue Samples From Women With Breast Cancer
NCT00897468 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 26
Last updated 2018-05-04
Summary
RATIONALE: Changing the genes in laboratory mice to create a living model of human breast cancer may help doctors learn more about breast cancer.
PURPOSE: This research study is developing mouse models of breast cancer using tissue samples that were previously collected from women with breast cancer.
Conditions
Interventions
- OTHER
-
laboratory biomarker analysis
Tissue samples will either be collected at the time of medically indicated surgical procedures or through research core biopsies. A sample of urine will also be obtained. Blood will be collected via venipuncture and lymphocytes (mononuclear cells) separated and processed as a source of normal DNA and normal cells.
- OTHER
-
medical chart review
patient chart review will occur in conjunction with patient data collection for final analyses.
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Vanderbilt-Ingram Cancer Center
lead OTHER
Principal Investigators
-
A. Bapsi Chakravarthy, MD · Vanderbilt-Ingram Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-02-28
- Primary Completion
- 2018-05-31
- Completion
- 2018-05-31
Countries
- United States
Study Locations
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