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Breast Stem Cells in Women at Average Risk and Increased Risk for Breast Cancer

NCT00923377 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3

Last updated 2017-07-02

No results posted yet for this study

Summary

Background:

* Research suggests that breast cancers may arise from a population of stem cells in the normal mammary gland that produce clones of cancer cells.
* Researchers are now trying to determine what events may initiate the formation of cancer cells.

Objectives:

* To look for and describe breast stem cells from normal breast tissue from women who do not have breast cancer.
* To compare the breast stem cells between women at increased risk for breast cancer and women at average risk for breast cancer.
* To show a relationship between the number and type of breast stem cells with the density (appearance) of the mammogram (breast x-ray).
* To make cell cultures (grow cells under controlled conditions) from the breast stem cells.

Eligibility:

-Women 18 years of age and older who are at average or increased risk for breast cancer.

Design:

Participants complete a health history questionnaire, family history questionnaire and risk assessment questionnaire.

* Participants have a mammogram and breast biopsy (surgical removal of a sample of breast tissue).
* Women who can become pregnant have a urine pregnancy test....

Conditions

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    lead NIH

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-03-23
Completion
2010-05-11

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00923377 on ClinicalTrials.gov