The Use of Oral Steroids in the Treatment of Cellulitis
NCT00893048 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2017-07-25
Summary
The prevalence of cellulitis in society is very high, as much as 3% of visits to Emergency Departments are for the treatment of this disease. The treatment of cellulitis varies depending on the severity. Low severity cases are treated with pain control and antibiotics by mouth and high severity are treated with antibiotics intravenously and pain control. The investigator's hypothesis is to see if the addition of steroids, which are known to decrease inflammation, will decrease the length of the disease process. If so, it will decrease the length of stay if IV antibiotics are needed, it will decrease duration of days out of work and decrease the overall pain control required and therefore patient satisfaction.
Conditions
- Cellulitis
- Erysipelas
Interventions
- DRUG
-
Prednisone, 60 mg, one time at time of diagnosis
- DRUG
-
Placebo Oral Tablet
Placebo
Sponsors & Collaborators
-
Milton S. Hershey Medical Center
lead OTHER
Principal Investigators
-
Scott Goldstein, DO · Penn State
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-01-15
- Primary Completion
- 2010-08-31
- Completion
- 2010-08-31
More Related Trials
-
A Study to Document the Effect of Petrolatum on Innate Immune Responses in the Skin
NCT02338076 ·Status: COMPLETED ·Phase: NA
-
Assessment of Suppression of Cutaneous Allergic Responses and Pruritis by Topical Minocycline
NCT04202263 ·Status: UNKNOWN ·Phase: PHASE2
-
A Double-Blind, Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of DX-2930 in Hereditary Angioedema Participants
NCT02093923 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety, Tolerability, and Dermal Reactogenicity Study of PDC-APB
NCT04853823 ·Status: UNKNOWN ·Phase: PHASE1
-
Using a Contact Dermatitis Model With Biologic Medications to Study Skin Inflammation
NCT05535738 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Evaluation of the Allergenicity of AMPHADASE INJECTION (Hyaluronidase Injection USP)
NCT01689363 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Fluid Retention Due to Superpotent Topical Corticosteroid
NCT02360202 ·Status: COMPLETED ·Phase: PHASE4
-
Study Assessing Impact of Dermatology Consultation for Patients Admitted With Cellulitis
NCT01706913 ·Status: COMPLETED ·Phase: NA
-
An Evaluation of the Reduction in Erythema in Adult Patients With Moderate to Severe Persistent Facial Erythema Associated With Rosacea
NCT03352323 ·Status: COMPLETED ·Phase: PHASE3
-
Penicillin Allergy Testing and Resensitization Rate
NCT03942731 ·Status: COMPLETED
-
Effectiveness of Polymyxin B Sulphate + Prednisolone + Benzocaine + Clioquinol in Acute and Sub-acute Dermatitis Eczematous
NCT01429701 ·Status: COMPLETED ·Phase: PHASE3
-
Pharmacokinetics and Distribution of Dapsone in Leucocytes After Single-dose and Multiple-dose Administration
NCT02493283 ·Status: COMPLETED ·Phase: PHASE1
-
Topical Corticosteroid App
NCT02921503 ·Status: COMPLETED ·Phase: NA
-
Silver Nitrate Application and Topical Corticosteroids for Hypergranulation Tissue
NCT02398539 ·Status: UNKNOWN ·Phase: PHASE4
-
Adding a Short Burst of Corticosteroid to the Conventional Treatment of H1 Antihistamines in Emergency Department.
NCT03296358 ·Status: COMPLETED ·Phase: NA
-
Utilizing Topical Sodium Hypochlorite to Ameliorate Radiation Dermatitis
NCT04630821 ·Status: TERMINATED ·Phase: NA
-
Allergic Disease Onset Prevention Study
NCT05003804 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Black Tea Compresses for Facial Eczema and Perioral Dermatitis
NCT02941432 ·Status: COMPLETED ·Phase: NA
-
Survey on Itch in Outpatients of a University Clinic
NCT03901443 ·Status: COMPLETED
-
Study to Evaluate the Influence of Hydrochlorothiazide on Dermal Photosensitivity and DNA Stability - a Pilot Study (HCTox Study)
NCT04654312 ·Status: COMPLETED ·Phase: PHASE1
-
Study of the Intradermal Injection of rHuPH20 or Placebo in Participants With Nickel Allergic Contact Dermatitis
NCT00928447 ·Status: COMPLETED ·Phase: PHASE2
-
SPT for Sensitization of Collagen Dressing
NCT06271993 ·Status: COMPLETED ·Phase: NA
-
A Study Assessing the Impact of Dermatology Consultation in Patients Presenting With Possible Cellulitis
NCT01795092 ·Status: COMPLETED ·Phase: NA
-
Drug Patch Tests in Patients With Severe Cutaneous Adverse Reaction to Drugs (SCARs)
NCT03176342 ·Status: UNKNOWN ·Phase: NA
-
Characterization of the Molecular Mechanisms Involved in Delayed-Type Hypersensitivity Reactions to House Dust Mite, Diphencyprone, Nickel, and Tuberculin Purified Protein Derivative in Healthy Volunteers
NCT03625219 ·Status: COMPLETED ·Phase: NA