MedTrace Logo

Evaluation of Fluid Retention Due to Superpotent Topical Corticosteroid

NCT02360202 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-02-05

No results posted yet for this study

Summary

Clinical observation frequently shows a paradoxical effect of topical corticosteroids in charge of a sudden melting of edema in the first days of treatment, which could be due to mobilization of extracellular. No study has shown the value of this measure in patients treated with topical steroids. This uncertainty, coupled with the observation of the paradoxical effects of topical steroids on edema are some patients that despite the systemic absorption of clobetasol propionate, a salt-free diet is not currently recommended practice.

Conditions

  • Bullous Pemphigoid

Interventions

PROCEDURE

Impedance analysis

Impedance analysis in patient with Bullous pemphigoid disease treated with clobetasol propionate. impedance analysis includes : fat measures, lean body mass, total body water, extracellular water phase angle

DRUG

Clobetasol Propionate cream treatment

clobetasol propionate treatment initiated following French recommendations

Sponsors & Collaborators

  • Société de Dermatologie Française

    collaborator OTHER

  • University Hospital, Rouen

    lead OTHER

Principal Investigators

  • Sophie Duvert Lehembre, Doctor · clinique dermatologique du chu de Rouen

Study Design

Allocation
NA
Purpose
PREVENTION
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-02-17
Primary Completion
2017-02-28
Completion
2017-02-28

Countries

  • France

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02360202 on ClinicalTrials.gov